Staffing and Capacity Planning for SARS-CoV-2 Monoclonal Antibody Infusion Facilities: A Performance Estimation Calculator Based on Discrete-Event Simulations

This study uses simulation to help plan staffing and capacity for COVID-19 monoclonal antibody infusion sites. It shows that bottlenecks are not just about nurses – check-in staff, physical space, and infusion time also strongly affect performance. Adding check-in staff can improve flow more than adding nurses in larger sites, and scheduled appointments work better than walk-ins when demand is manageable. Shortening infusion or preparation time can greatly reduce delays when systems are near capacity. The study produced a web-based planning tool that helps sites test scenarios and make better staffing and resource decisions during surges.